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Research Results in Pharmacology

Volume 7, Issue №1, 2021 PDF
Uncategorized

Renoprotective Effect of Carbamylated Darbepoetin and Udenafil in Ischemia-reperfusion of Rat Kidney due to the Effect of Preconditioning and Inhibition of Nuclear Factor Kappa B
 

Introduction: Acute kidney injury is a widespread complication in hospitalized patients, with a high mortality rate and long-term complications affecting prognosis and quality of life and with high human ...

Experimental Assessment of Immunoreactivity Indices and Effectiveness of Pharmacotherapy Schemes in Surgical Models of Acute Pancreatitis of Various Severity
 

Introduction: The investigation was aimed at assessment of immunoreactivity in the experimental groups of animals and evaluation of effectiveness of different combinations of pharmacological drugs used in the ...

ACTH6-9-PGP Improves Memory Consolidation Processes in Rats
 

Introduction: The His-Phe-Arg-Trp sequence corresponding to the 6-9th amino acid residue of the adrenocorticotropic hormone molecule (ACTH6-9) is the critical pharmacophore of all endogenous melanocortin receptor agonists. In order to ...

In Search of New Brain Biomarkers of Stress
 

The aim of the study was to investigate the level of ghrelin in various brain structures during a stress response in Zebrafish to a predator, to evaluate ...

3D Organotypic Cell Structures for Drug Development and Microorganism-Host Interaction Research

Introduction: The article describes a new method of tissue engineering, which is based on the use of three-dimensional multicellular constructs consisting of stem cells that mimic the native tissue ...

N-acetylcysteine relieves neurologic signs of acute ethanol hangover in rats
 

Introduction: Alcohol abuse is one of the grave social and medical problems in many countries, including Russia. Alcohol not only negatively affects health, social and family relationships, but ...