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PHARMACOLOGYCAL REVIEWS

LIPID DISTRESS-SYNDROME AND PROSPECTS OF ITS CORRECTION BY STATINES

Volume 3, Issue №3, 2017
Endothelial dysfunction in peritonitis: The formed concept of lipid distress syndrome (LDS) allows us to develop a working hypothesis on the key role of endothelial dysfunction in the aggressive ...

STATE SUPPORT FOR RESEARCH IN PHARMACOLOGY: AN ANALYSIS OF FOREIGN AND DOMESTIC EXPERIENCE

Volume 3, Issue №3, 2017
Introduction: The goal of research was to analyze the management of innovative activities for innovative medicines market launch in Russia and abroad. Materials and methods: In the study ...

NANOPARTICLES AS AGENTS FOR TARGETED DELIVERY IN THE TREATMENT OF VASCULAR PATHOLOGIES

Volume 3, Issue №2, 2017
Inflammation in the pathogenesis of cardiovascular diseases. Inflammation is the cornerstone of CVD. Systemic inflammation can lead to activation of the endothelium characterized by increased expression of endothelial adhesion ...

PHYSICO-CHEMICAL PROPERTIES OF MONTMORILLONITE CLAYS AND THEIR APPLICATION IN CLINICAL PRACTICE (REVIEW)

Volume 3, Issue №2, 2017
The review is devoted to the medical application of montmorillonite clay minerals. Properties and mechanisms of action of enterosorbents. The properties of the enterosorbents include an absorption capacity and ...

NUCLEAR FACTOR KAPPA B AS A POTENTIAL TARGET FOR PHARMACOLOGICAL CORRECTION ENDOTHELIUM-ASSOCIATED PATHOLOGY

Volume 3, Issue №1, 2017
The nuclear factor kappa B (NF-κB) is one of transcription factors. A high interest in studying the biological role of the signal system and its contribution to the development ...

DEVELOPMENT PERSPECTIVES OF NEW GENERATION MEDICATIONS BASED ON THE REDOX SYSTEM REGULATORS

Volume 2, Issue №4, 2016
This survey paper describes the necessity of the development of new medications influencing the body redox-potential. It supports the most pressing branch of pharmacology, which coincides with logically relevant attempts ...

METABOLIC CARDIOPROTECTION: NEW CONCEPTS IN IMPLEMENTATION OF CARDIOPROTECTIVE EFFECTS OF MELDONIUM

Volume 2, Issue №3, 2016
Recent studies confirm the need to find means to correct ischemic / reperfusion injury due to the hemodynamic medicine, which are already known do not have the proper cardioprotective effects. ...

PARADIGM OF MODERN PHARMACOLOGY: DEVELOPMENT AND CURRENT APPROACHES

Volume 2, Issue №3, 2016
The article focuses on the current approach to understanding pharmaceutical products’ effect. It describes a paradigm shift in views on pharmaceutical action in correlation to the processes occurring under pathology. ...

THE POSSIBILITY OF ADMINISTRATION OF GLUTAMATE RECEPTORS ANTAGONISTS IN THE TREATMENT OF PARKINSON'S DISEASE

Volume 2, Issue №3, 2016
Parkinson's disease is the slow-progressing chronic neurodegenerative disease. It caused by the progressive destruction and death of neurons that produce the neurotransmitter dopamine, primarily in the substantia nigra and also ...

THYMOSIN β4 AS BASIS FOR CREATION OF A REPARATION PREPARATION OF NEW GENERATION

Volume 2, Issue №3, 2016
In article is narrated about Thymosin β4. Its structure, a number of strategically important properties and opportunities is described. The list of researches and achievements over the past few years ...
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