PHARMACOLOGYCAL REVIEWS
Amphotericin B from Antifungal to Antiviral Therapy: Promising Modern Therapeutic Branch
Volume 6, Issue №2, 2020
Introduction: Amphotericin B (AmB) which belongs to the polyene group has a wide spectrum in vitro and in vivo antimicrobial activity against fungi and parasites, but resistance to ...
Modern Approaches to the Treatment of Chronic Polypous Rhinosinusitis
Volume 6, Issue №2, 2020
Introduction: Today, chronic polypous rhinosinusitis (CPR) occupies a special place among otolaryngological diseases, the incidence rate of which increases every year. To date, the main causes of chronic polypous rhinosinusitis ...
Search for new pharmacological targets for increasing the efficiency of correction of cardiovascular diseases
Volume 5, Issue №3, 2019
Introduction: Cardiovascular disease (CVD) is the leading cause of death worldwide: no other reason causes as many deaths a year as CVD. An estimated 17.9 million people died of CVD in 2016, accounting ...
STATE SUPPORT FOR RESEARCH IN PHARMACOLOGY: AN ANALYSIS OF FOREIGN AND DOMESTIC EXPERIENCE
Volume 3, Issue №3, 2017
Introduction: The goal of research was to analyze the management of innovative activities for innovative medicines market launch in Russia and abroad. Materials and methods: In the study ...
LIPID DISTRESS-SYNDROME AND PROSPECTS OF ITS CORRECTION BY STATINES
Volume 3, Issue №3, 2017
Endothelial dysfunction in peritonitis: The formed concept of lipid distress syndrome (LDS) allows us to develop a working hypothesis on the key role of endothelial dysfunction in the aggressive ...
NUCLEAR FACTOR KAPPA B AS A POTENTIAL TARGET FOR PHARMACOLOGICAL CORRECTION ENDOTHELIUM-ASSOCIATED PATHOLOGY
Volume 3, Issue №1, 2017
The nuclear factor kappa B (NF-κB) is one of transcription factors. A high interest in studying the biological role of the signal system and its contribution to the development ...
PHYSICO-CHEMICAL PROPERTIES OF MONTMORILLONITE CLAYS AND THEIR APPLICATION IN CLINICAL PRACTICE (REVIEW)
Volume 3, Issue №2, 2017
The review is devoted to the medical application of montmorillonite clay minerals. Properties and mechanisms of action of enterosorbents. The properties of the enterosorbents include an absorption capacity and ...
NANOPARTICLES AS AGENTS FOR TARGETED DELIVERY IN THE TREATMENT OF VASCULAR PATHOLOGIES
Volume 3, Issue №2, 2017
Inflammation in the pathogenesis of cardiovascular diseases. Inflammation is the cornerstone of CVD. Systemic inflammation can lead to activation of the endothelium characterized by increased expression of endothelial adhesion ...
SEARCH OF NEW PHARMACEUTICALS ON THE BASIS OF DARBEPOETIN IN THE TREATMENT OF ISCHEMIC STROKE (REVIEW OF LITERATURE)
Volume 3, Issue №1, 2017
The article contains the analysis of medical and biological publications from the global database created by the National Centre for Biology Information (NCBI), an intramural biotechnological division of the US ...
DEVELOPMENT PERSPECTIVES OF NEW GENERATION MEDICATIONS BASED ON THE REDOX SYSTEM REGULATORS
Volume 2, Issue №4, 2016
This survey paper describes the necessity of the development of new medications influencing the body redox-potential. It supports the most pressing branch of pharmacology, which coincides with logically relevant attempts ...
THE POSSIBILITY OF ADMINISTRATION OF GLUTAMATE RECEPTORS ANTAGONISTS IN THE TREATMENT OF PARKINSON'S DISEASE
Volume 2, Issue №3, 2016
Parkinson's disease is the slow-progressing chronic neurodegenerative disease. It caused by the progressive destruction and death of neurons that produce the neurotransmitter dopamine, primarily in the substantia nigra and also ...
PARADIGM OF MODERN PHARMACOLOGY: DEVELOPMENT AND CURRENT APPROACHES
Volume 2, Issue №3, 2016
The article focuses on the current approach to understanding pharmaceutical products’ effect. It describes a paradigm shift in views on pharmaceutical action in correlation to the processes occurring under pathology. ...
METABOLIC CARDIOPROTECTION: NEW CONCEPTS IN IMPLEMENTATION OF CARDIOPROTECTIVE EFFECTS OF MELDONIUM
Volume 2, Issue №3, 2016
Recent studies confirm the need to find means to correct ischemic / reperfusion injury due to the hemodynamic medicine, which are already known do not have the proper cardioprotective effects. ...
THYMOSIN β4 AS BASIS FOR CREATION OF A REPARATION PREPARATION OF NEW GENERATION
Volume 2, Issue №3, 2016
In article is narrated about Thymosin β4. Its structure, a number of strategically important properties and opportunities is described. The list of researches and achievements over the past few years ...
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