Research result: pharmacology and clinical pharmacology

Выпуск №2 (7) 2017
EXPERIMENTAL PHARMACOLOGY

PLEYOTROPIC ANTIAGGREGANT EFFECTS OF AN INNOVATIVE ANTIARRHYTHMIC OF CLASS III SS-68, AN INDOLE DERIVATIVE

Background: A new indole derivative with the lab code-number SS-68 demonstrates a significant antiarrhythmic (anti-fibrillation) activity associated with the predominant influence on potassium and calcium conductivity of cardiomyocytes plasmalemmas. ...

EXPERIMENTAL RATIONALE FOR THE USE OF FLUIDS WITH DIFFERENT REDOX POTENTIAL AS A BASIS FOR INFUSION THERAPY

Introduction: The hypothesis is that a change in the redox potential (Red-Ox) of infusion solutions can increase their pharmacological efficacy. Objectives: To study the parameters of redox potential (ORP ...

CLINICAL PHARMACOLOGY

PHARMACOLOGICAL CORRECTION OF FETOPLACENTAL INSUFFICIENCY WITH FETAL GROWTH RETARDATION SYNDROME

Introduction: fetoplacental insufficiency (FPI) is an important problem of obstetrics. This pathological condition leads to the development of fetal growth retardation syndrome (FGRS). Any standard treatment regimens cannot exist ...

THE METHODOLOGY OF ASSESSING THE EFFECTIVENESS OF THE THERAPY

Objectives: To substantiate the methodology for assessing the effectiveness of drug therapy, based on the effect of therapy not only on the target organ or function, but also on ...

PHARMACOLOGYCAL REVIEWS

NANOPARTICLES AS AGENTS FOR TARGETED DELIVERY IN THE TREATMENT OF VASCULAR PATHOLOGIES

Inflammation in the pathogenesis of cardiovascular diseases. Inflammation is the cornerstone of CVD. Systemic inflammation can lead to activation of the endothelium characterized by increased expression of endothelial ...

PHYSICO-CHEMICAL PROPERTIES OF MONTMORILLONITE CLAYS AND THEIR APPLICATION IN CLINICAL PRACTICE (REVIEW)

The review is devoted to the medical application of montmorillonite clay minerals. Properties and mechanisms of action of enterosorbents. The properties of the enterosorbents include an absorption capacity and ...