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STUDY OF THE MICROCIRCULATION LEVEL IN BONE WITH OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES DURING THERAPY WITH RECOMBINANT ERYTHROPOIETIN, ROSUVASTATIN AND THEIR COMBINATIONS

The experiment was carried out in female white Wistar rats. The effects of recombinant erythropoietin, rosuvastatin and their combination were investigated based on the blood supply to the bone after a modelled experimental osteoporosis. It was found that the studied drugs prevent decrease of bone microcirculation in cases of osteoporosis and in callus tissue in experimental osteoporotic fractures, positively influencing the course of reparative regeneration of bone tissue.

DOI: 10.18413/2500-235X-2015-1-4-57-60
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