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Research Result: Pharmacology and Clinical Pharmacology

Том 4, Выпуск №2, 2018

ENDOTHELOTROPIC ACTIVITY OF 4-HYDROXY-3,5-DI-TRET-BUTYLCINNAMIC ACID IN THE CONDITIONS OF EXPERIMENTAL CEREBRAL ISCHEMIA

Introduction: The aim of the study was to evaluate the endothelioprotective activity of 4-hydroxy-3,5-di-tret-butylcinnamic acid in conditions of experimental cerebral ischemia. Materials and Methods: The brain ischemia was ...

IMIDAZOLINE RECEPTORS AGONISTS: POSSIBLE MECHANISMS OF ENDOTHELIOPROTECTION

Imidazoline receptor agonists are one of the groups of contemporary antihypertensive drugs with the pleiotropic cardiovascular effects. In this review, the historical, physiological, pathophysiological aspects concerning imidazoline ...

ASSESSMENT OF PHARMACOLOGICAL ACTIVITY AND BIOAVAILABILITY OF THE NEW DERIVATIVE 1,3,4-THIADIAZOLE

Introduction: Acexazolamide is a new derivative of 1,3,4-thiadiazole and acexamic acid. Materials and Methods: In animal experiments, acute toxicity, pharmacological activity and bioavailability of acexazolamide were ...