PHARMACOLOGYCAL REVIEWS
Амфотерицин B от противогрибковой до противовирусной терапии: перспективное направление современной терапии
Том 6, Выпуск №2, 2020
Введение: Амфотерицин B (AmB), который принадлежит к группе полиенов, обладает широким спектром антимикробной активности in vitro и in vivo против грибков и паразитов, но устойчивость к AmB встречается редко, несмотря ...
Изучение максимальной толерантной дозы и обезболивающей активности пептида РТ1
Том 5, Выпуск №3, 2019
Введение: В статье представлены результаты изучения максимальной толерантной дозы (МТД) и обезболивающей активности пептида РТ1, выделенного из яда паука Alopecosa marikovskyi. PT1 является первым соединением полипептидной природы, способным оказывать селективное ...
STATE SUPPORT FOR RESEARCH IN PHARMACOLOGY: AN ANALYSIS OF FOREIGN AND DOMESTIC EXPERIENCE
Том 3, Выпуск №3, 2017
Introduction: The goal of research was to analyze the management of innovative activities for innovative medicines market launch in Russia and abroad. Materials and methods: In the study ...
LIPID DISTRESS-SYNDROME AND PROSPECTS OF ITS CORRECTION BY STATINES
Том 3, Выпуск №3, 2017
Endothelial dysfunction in peritonitis: The formed concept of lipid distress syndrome (LDS) allows us to develop a working hypothesis on the key role of endothelial dysfunction in the aggressive ...
NUCLEAR FACTOR KAPPA B AS A POTENTIAL TARGET FOR PHARMACOLOGICAL CORRECTION ENDOTHELIUM-ASSOCIATED PATHOLOGY
Том 3, Выпуск №1, 2017
The nuclear factor kappa B (NF-κB) is one of transcription factors. A high interest in studying the biological role of the signal system and its contribution to the development ...
PHYSICO-CHEMICAL PROPERTIES OF MONTMORILLONITE CLAYS AND THEIR APPLICATION IN CLINICAL PRACTICE (REVIEW)
Том 3, Выпуск №2, 2017
The review is devoted to the medical application of montmorillonite clay minerals. Properties and mechanisms of action of enterosorbents. The properties of the enterosorbents include an absorption capacity and ...
NANOPARTICLES AS AGENTS FOR TARGETED DELIVERY IN THE TREATMENT OF VASCULAR PATHOLOGIES
Том 3, Выпуск №2, 2017
Inflammation in the pathogenesis of cardiovascular diseases. Inflammation is the cornerstone of CVD. Systemic inflammation can lead to activation of the endothelium characterized by increased expression of endothelial ...
SEARCH OF NEW PHARMACEUTICALS ON THE BASIS OF DARBEPOETIN IN THE TREATMENT OF ISCHEMIC STROKE (REVIEW OF LITERATURE)
Том 3, Выпуск №1, 2017
The article contains the analysis of medical and biological publications from the global database created by the National Centre for Biology Information (NCBI), an intramural biotechnological division of the US ...
DEVELOPMENT PERSPECTIVES OF NEW GENERATION MEDICATIONS BASED ON THE REDOX SYSTEM REGULATORS
Том 2, Выпуск №4, 2016
This survey paper describes the necessity of the development of new medications influencing the body redox-potential. It supports the most pressing branch of pharmacology, which coincides with logically relevant attempts ...
THYMOSIN β4 AS BASIS FOR CREATION OF A REPARATION PREPARATION OF NEW GENERATION
Том 2, Выпуск №3, 2016
In article is narrated about Thymosin β4. Its structure, a number of strategically important properties and opportunities is described. The list of researches and achievements over the past few years ...
PARADIGM OF MODERN PHARMACOLOGY: DEVELOPMENT AND CURRENT APPROACHES
Том 2, Выпуск №3, 2016
The article focuses on the current approach to understanding pharmaceutical products’ effect. It describes a paradigm shift in views on pharmaceutical action in correlation to the processes occurring under pathology. ...
METABOLIC CARDIOPROTECTION: NEW CONCEPTS IN IMPLEMENTATION OF CARDIOPROTECTIVE EFFECTS OF MELDONIUM
Том 2, Выпуск №3, 2016
Recent studies confirm the need to find means to correct ischemic / reperfusion injury due to the hemodynamic medicine, which are already known do not have the proper cardioprotective effects. ...
THE POSSIBILITY OF ADMINISTRATION OF GLUTAMATE RECEPTORS ANTAGONISTS IN THE TREATMENT OF PARKINSON'S DISEASE
Том 2, Выпуск №3, 2016
Parkinson's disease is the slow-progressing chronic neurodegenerative disease. It caused by the progressive destruction and death of neurons that produce the neurotransmitter dopamine, primarily in the substantia nigra and also ...
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