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  • ContentsContents
  • Article InfoArticle Info
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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Effect of SS-68 on κ1-opioid receptors
    • The study of the negative chronotropic action of SS-68 in the intact atrial and ventricular myocardium and against the background of its cholinergic stimulation in vitro
    • The effect of SS-68 on ionic homeostasis of resting and stimulated (intact and ischemic) cardiomyocytes
    • The effect of SS-68 on Na+-, Ca2+- and K+-ionic currents and AP
  • Results and discussion
    • Effect of SS-68 on κ1-opioid receptors in experiments using molecular docking
    • Effect of SS-68 on resting and stimulated (intact and ischemic) rat cardiomyocytes on ionic homeostasis
    • Effect on Na+-channels
    • Effect on Ca2+-channels
    • Impact on K+-channels
    • Study of the negative chronotropic action of SS-68 in the intact atrial and ventricular myocardium and against the background of its cholinergic stimulation in vitro
    • The effect of SS-68 on Na+, Ca2+ and K+ transmembrane ion currents and the action potential of isolated unidentified gastropod neurons and rat hippocampal neuron cultures
    • Effect of SS-68 on ionic currents and the action potential of rat hippocampal neuron cultures
      • The effect of SS-68 on induced AP in the hippocampal neurons
      • The effect of SS-68 on ion currents in the mode of fixing the potential on the neuron membrane
  • Discussion
    • Effect on opioid receptors
  • Conclusions
  • References
  • Author contributions
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