Research Article
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Article title
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Abstract
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Keywords
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Introduction
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Materials and methods
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Effect of SS-68 on κ1-opioid receptors
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The study of the negative chronotropic action of SS-68 in the intact atrial and ventricular myocardium and against the background of its cholinergic stimulation in vitro
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The effect of SS-68 on ionic homeostasis of resting and stimulated (intact and ischemic) cardiomyocytes
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The effect of SS-68 on Na+-, Ca2+- and K+-ionic currents and AP
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Results and discussion
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Effect of SS-68 on κ1-opioid receptors in experiments using molecular docking
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Effect of SS-68 on resting and stimulated (intact and ischemic) rat cardiomyocytes on ionic homeostasis
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Effect on Na+-channels
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Effect on Ca2+-channels
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Impact on K+-channels
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Study of the negative chronotropic action of SS-68 in the intact atrial and ventricular myocardium and against the background of its cholinergic stimulation in vitro
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The effect of SS-68 on Na+, Ca2+ and K+ transmembrane ion currents and the action potential of isolated unidentified gastropod neurons and rat hippocampal neuron cultures
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Effect of SS-68 on ionic currents and the action potential of rat hippocampal neuron cultures
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The effect of SS-68 on induced AP in the hippocampal neurons
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The effect of SS-68 on ion currents in the mode of fixing the potential on the neuron membrane
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Discussion
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Effect on opioid receptors
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Conclusions
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References
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Author contributions