Compliance with ethical and regulatory requirements in the performance of the research

Experimental animals

Assessment of the level of microcirculation when simulating the pathology

Biochemical markers of acute kidney injury

Biochemical analysis of urine. Calculation of endogenous creatinine clearance (glomerular filtration rate) and fractional excretion of sodium

Morphological methods for assessing changes in the kidneys

Study design. The choice of administration modes for pharmacological agents

Statistical processing of research results

Nephroprotective effects of asialoerythropoietin and selective inhibitor of arginase II KUD975 in experimental renal ischemia

Nephroprotective effects of a combination of asialoerythropoietin and a selective inhibitor of arginase II in experimental renal ischemia

The role of eNOS and K+ATP channels in inducing the nephroprotective effects of asialoerythropoietin and selective inhibitor of arginase II in experimental ischemia-reperfusion of the kidneys