Molecular docking studies of N-substituted 4-methoxy-6-oxo-1-aryl-pyridazine-3-carboxamide derivatives as potential modulators of glutamate receptors


	Spatial structure of the mGlu8 receptor with an L-AP4 agonist at the binding site А. 3D MGlu8 structure with an L-AP4 agonist in the binding site B. Interaction of L-AP4 with amino acid residues of the binding site. Hydrophilic bonds are indicated by blue lines, hydrophobic bonds are indicated by gray lines.

Part of: Severina HI, Georgiyants VA, Kovalenko SM, Avdeeva NV, Yarcev AI, Prohoda SN (2020) Molecular docking studies of N-substituted 4-methoxy-6-oxo-1-aryl-pyridazine-3-carboxamide derivatives as potential modulators of glutamate receptors. Research Results in Pharmacology 6(1): 69-82. https://doi.org/10.3897/rrpharmacology.6.52026