Molecular docking, ADMET study and in vivo pharmacological research of N-(3,4-dimetoxyphenyl)-2-{[2-methyl-6-(pyridine-2-yl)-pyrimidin-4-yl]thio}acetamide as a promising anticonvulsant

Research Article

Research Results in Pharmacology 6(2): 27-41
https://doi.org/10.3897/rrpharmacology.6.53332 (19 Jun 2020)

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Article title
Abstract
Keywords
Introduction
Materials and methods
- Molecular docking study
- ADMET
- Chemistry
- Pharmacological studies
- Acute toxicity study
- Neurotoxicity study ()
- Rotarod test
- Open-field test
Results and discussion
- Docking study
- ADMET analysis
- Chemistry
- Pharmacological study
- Anticonvulsant activity on the model of MES-induced seizures
- Determination of the average effective dose of Epirimil
- Acute toxicity
- Neurotoxicity
- The influence on psycho-emotional state
Conclusion
Conflict of interest
References
Author contributions

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