Laboratory animals

Focal cerebral ischemia model

Study design

Biomaterial sampling

Necrosis zone evaluation

Respirometric analysis

Evaluation of mitochondrial permeability transition pore opening

Mitochondrial membrane potential evaluation

Evaluation of citrate synthase activity

Evaluation of the calcium ions concentration

Statistical analysis

The results of the L-carnitine effect on the change in the total respiratory function of neuronal mitochondria in rats under the cerebral ischemia conditions

The results of the L-carnitine effect on the change in the activity of anaerobic processes in the rats’ brain under the cerebral ischemia conditions

The results of the L-carnitine effect on changes in the activity of mitochondrial complexes in rats brain under the cerebral ischemia conditions

The results of the L-carnitine effect on the change of the citrate synthase activity in rats’ brain under the cerebral ischemia conditions

The results of the L-carnitine effect on changes in the mitochondrial membrane potential in rats’ brain under the cerebral ischemia conditions

The results of the L-carnitine effect on the change in the latent time of mitochondrial permeability transitional pore opening in rats’ brain under the cerebral ischemia conditions

The results of the L-carnitine effect on changes in the concentration of calcium in the brain supernatant in rats under the cerebral ischemia conditions

The results of the L-carnitine effect on the change in the size of the brain necrosis zone in rats under the cerebral ischemia conditions