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Research Article
Research Results in Pharmacology 7(1): 1-19
https://doi.org/10.3897/rrpharmacology.7.63059 (28 Jan 2021)
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  • ContentsContents
  • Article InfoArticle Info
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  • Article title
  • Abstract
  • Keywords
  • Introduction
    • Research aim
  • Materials and methods
    • Simulation of bilateral renal ischemia-reperfusion
    • Renal microcirculation level
    • Laboratory methods for assessing the renal function
    • Morphological methods for assessing changes in the kidneys
    • Stimulation and determination of the expression of phosphorylated NF-κB in peripheral blood mononuclear cells
    • Research design. Choice of administration modes for pharmacological agents
    • Statistical processing of research results
  • Results and discussion
    • Selection of the optimal duration of renal ischemia and assessment of the development of acute kidney injury in the simulation of bilateral renal ischemia-reperfusion
    • Renoprotective effects of carbamylated darbepoetin in bilateral renal ischemia-reperfusion simulation
    • Renoprotective effects of udenafil in modelling bilateral renal ischemia-reperfusion
    • Renoprotective effects of the combination of carbamylated darbepoetin and udenafil in the simulation of bilateral renal ischemia-reperfusion
    • The role of ATP-dependent potassium channels in the realization of the renoprotective effects of carbamylated darbepoetin and udenafil in experimental renal ischemia-reperfusion
    • Role of nuclear factor kappa B in the realization of the renoprotective effects of carbamylated darbepoetin and udenafil in experimental renal ischemia-reperfusion
  • Conclusion
  • Conflict of interests
  • Acknowledgements
  • References
  • Author’s contribution
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