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Research Article
Research Results in Pharmacology 7(3): 33-39
https://doi.org/10.3897/rrpharmacology.7.72784 (17 Sep 2021)
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  • Article InfoArticle Info
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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Design and manufacture of genetic construct
    • Animals and keeping conditions
    • Solutions and media
    • Transgenic animals creation
    • In vitro fertilization
    • Genotyping
    • Copy number determination
    • Ethical approval
  • Results
    • Primary transgenic mice creation with mutant Polg gene inducible expression
    • Obtaining two independent animal lines with inducible expression of the mutant Polg gene
    • Transgene copies in three Polg strain variants
    • GFP fluorescence of Polg*CMV pup
  • Discussion
  • Conclusion
  • Conflict of interest
  • Funding
  • References
  • Author contributions
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