Research Article
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Article title
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Abstract
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Keywords
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Introduction
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Materials and methods
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Animals
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Test-objects
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Study design
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Biomaterial preparation
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Acute toxicity determination
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Cerebral ischemia model
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Morris water maze test
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Assessment of changes in the rate of cerebral blood flow
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Necrosis zone evaluation
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Assessment of the activity of mitochondrial complexes
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Measurement of citrate synthase activity
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Determination of lactic acid concentration
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Determination of pyruvic acid concentration
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Determination of ATP concentration
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Statistical analysis
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Results
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Assessment of acute toxicity of the test extract
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Evaluation of the effect of the test extract on changes in the behavior of animals in the Morris water maze test
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Evaluation of the effect of the test extract on the change in the cerebral blood flow rate, the size of the brain necrosis zone, and the concentrations of lactic and pyruvic acids in the blood serum of rats
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Evaluation of the effect of the test extract on the change in the activity of the complexes of the mitochondrial respiratory chain, citrate synthase, and the concentration of ATP in the brain of rats
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Discussion
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Conclusion
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Conflict of interest
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Acknowledgements
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References
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Author Contributions