Research Article
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Article title
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Abstract
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Keywords
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Introduction
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Materials and methods
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Experimental animals
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Pharmaceutical substances and reagents
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Development methods and physico-chemical research methods
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Acute toxicity study
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Gastroprotective effect study
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Experimental design for NSAID-gastropathy
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Scheme 1”prevention”: screening for preventive gastroprotective action
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Scheme 2 “curative”: study of the pharmacotherapeutic effect (assessment of the gastroprotective effect and the prevention of manifestations of organotropic toxicity)
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Experimental design for ethanol-induced ulcerogenesis
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Experimental design for stress-induced ulcerogenesis
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Planimetric method for determining the area of ulcers on the gastric mucosa
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Laboratory research methods
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Pathoanatomical and histological research methods
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Statistical analysis
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Results and discussion
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Development and evaluation of a chitosan-based gel containing dexpanthenol
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Acute oral toxicity evaluation
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Screening of the preventive gastroprotective effect of chitosan-based gel containing dexpanthenol in NSAID-gastropathy model
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Comparative evaluation of the gastroprotective effect of chitosan-based gel containing dexpanthenol in ethanol-induced ulcerogenesis
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Comparative evaluation of the gastroprotective effect of chitosan-based gel containing dexpanthenol in stress-induced ulcerogenesis
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Study of the pharmacotherapeutic effect of chitosan-based gel containing dexpanthenol in NSAID-gastropathy model (curative scheme)
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Conclusion
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Acknowledgements
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References
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Author contributions