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  • ContentsContents
  • Article InfoArticle Info
  • CitationCitation
  • MetricsMetrics
  • CommentComment
  • RelatedRelated
  • FigsFigs
  • TabsTabs
  • RefsRefs
  • CitedCited
  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Risk factors for development of osteoarthritis
  • Etiopathogenesis of osteoarthritis
  • Materials and methods
  • Results and discussion
    • Agents targeting articular cartilage
      • MMP inhibitors
      • Aflapin
      • Pycnogenol
      • ADAMTS inhibitors
      • GSK2394002
      • Growth factors
      • Sprifermin
      • GEC-TGF-β
      • BMP
      • Cathepsin K inhibitors
      • Wnt/β-catenin signalling pathway inhibitors
      • VEGF inhibitors
      • Diacerein
      • NO inhibitors
      • COX-2 inhibitors
    • Agents targeting inflammation
      • TNF-α inhibitors
      • Adalimumab
      • Infliximab
      • DLX105
      • IL-1 inhibitors
      • Canakinumab
      • Anakinra
      • Gevokizumab
      • ABT-981
      • Methotrexate
      • Polyphenols
      • Limonene and Myrcene
    • Agents targeting subchondral bone
      • Bisphosphanates
      • Strontium ranelate
      • SERMs (Selective Estrogen Receptor Modulators)
    • Agents targeting pain
      • Nerve growth factor (NGF) inhibitors
      • Tanezumab
      • Duloxetine
      • FX006
      • Tapentadol
      • Cannabidiol (CBD)
      • Platelet rich plasma
  • Conclusion
  • References
  • Author contributions
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