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Research Article
Research Results in Pharmacology 8(4): 185-196
https://doi.org/10.3897/rrpharmacology.8.91390 (22 Dec 2022)
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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Animals
    • Drugs and chemicals
    • Hemocoel injections
    • Rolling behavior assay
    • Infrared radiation intensity
    • Measurement of water droplet temperature
    • Effects of analgesic substances on infrared nociception
    • Effects of analgesic substances on locomotor behavior
    • Induction of thermal nociceptive sensitization
    • Effects of ASA and DXM on infrared-induced nociceptive sensitization
    • Statistical analysis
  • Results and discussion
    • Choice of infrared radiation intensity
    • Water droplet temperature of rolling behavior
    • Morphine antinociceptive effect in D. melanogaster larvae
    • Dipyrone acts as an antinociceptive substance in D. melanogaster larvae
    • Infrared-induced nociceptive sensitization
    • ASA reversed infrared-induced nociceptive sensitization
    • Short-term and long-term effects of DXM in infrared-induced nociceptive sensitization
    • Locomotor behaviors of D. melanogaster larvae were not affected by analgesic substances
  • Conclusion
  • Funding
  • Conflict of interest
  • References
  • Author contributions
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