Nutritional supplementation of the pharmacotherapy of prostate diseases

Authors

DOI:

https://doi.org/10.3897/rrpharmacology.7.67465

Abstract

Introduction: Nutritional supplementation is an integral part of modern pharmacotherapeutic strategies for prostate diseases with different levels of evidence for specific nutrients.

Provitamin A (beta-carotene), vitamin A (retinol) and prostate diseases. Their effects have not been sufficiently studied, and the available data are conflicting to recommend them as a nutritional supplement.

Vitamin E (tocopherol) and prostate diseases. Its effects have not been sufficiently studied, and the available data are conflicting to recommend it as a nutritional supplement.

Vitamin C (ascorbic acid) and prostate diseases. Its effects have not been sufficiently studied, and the available data are conflicted to recommend it as a nutritional supplement.

Vitamin K and prostate diseases. Its effects have not been sufficiently studied, and the available data are conflicted to recommend it as a nutritional supplement.

Vitamin D and prostate diseases. The evidence base of the vitamin Dprostatotropic effects has been accumulated, which allows us to consider its deficiency replacement as an effective nutritional supplement in prostate diseases.

Omega-3 PUFAs and prostate diseases. They have universal physiological effects; however, the evidence base for their recommendation as a nutritional supplement for prostate diseases is still insufficient.

Zinc and prostate diseases. Positive effects of zinc on the prostate gland are known for a fact and allow us to recommend it as a nutritional supplement for prostate diseases.

Selenium and prostate diseases. The reliably proven positive effects of selenium on the prostate gland allow us to recommend it as a nutritional supplement for prostate diseases.

Magnesium and prostate diseases. Its effects have not been sufficiently studied, and the available data are conflicting to recommend it as a nutritional supplement.

Keywords:

prostate diseases, nutritional supplementation, vitamin A, vitamin E, vitamin K, vitamin D, Omega-3 polyunsaturated fatty acids, zinc, selenium, magnesium

Author Contribution

Oleg I. Bratchikov, Kursk State Medical University

Doctor Habil. of Medical Sciences, Professor, Head of the Department of Urology, e-mail: bratov45@mail.ru, ORCID ID http://orcid.org/0000-0002-0906-9851. The author developed the research design, analyzed the obtained data and was engaged in the article writing.

Igor A. Tyuzikov, Tandem-Plus Medical Center

Candidate of Medical Sciences, Professor, Urologist, e-mail: phoenix-67@list.ru, ORCID ID http://orcid.org/0000-0001-6316-9020. The author obtained the data for analysis, analyzed the obtained data, and was engaged in the article writing.

Pavel A. Dubonos, Kursk State Medical University

Postgraduate Student, Department of Urology, e-mail: v-utkin@rambler.ru, ORCID ID http://orcid.org/0000-0001-9265-9467. The author reviewed the relevant literature and obtained the data for analysis.

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Published

07-07-2021

How to Cite

Bratchikov OI, Tyuzikov IA, Dubonos PA (2021) Nutritional supplementation of the pharmacotherapy of prostate diseases. Research Results in Pharmacology 7(3): 1–14. https://doi.org/10.3897/rrpharmacology.7.67465

Issue

Section

Review article