The effect of humoral factors released by hypoperfused placenta on fetal development

Авторы

  • V.V. Gureev Belgorod State National Research University
  • O.Ye. Antseferova Belgorod State National Research University
  • T.I. Lokteva Belgorod State National Research University
  • A.A. Dolzhikov Belgorod State National Research University

DOI:

https://doi.org/10.18413/2500-235X-2015-1-4-39-44

Аннотация

Simulation of hypoperfusion of the right uterine horn in rats on the 14th day of pregnancy resulted in disruption of microcirculation in placentas of the left uterine horn, decrease of fetal weight and length as well as in fetal death after implantation. The obtained data complement the overall understanding of the pathogenesis of preeclampsia and placental insufficiency and create preconditions for development of new areas of creation of effective drugs for treatment and prevention of these pathologies.

Ключевые слова:

rats, preeclampsia, placental insufficiency, placental ischemia, fetal hypoplasia

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Вклад авторов

V.V. Gureev, Belgorod State National Research University

PhD in Medical Sciences, Associate Professor, Department of Pharmacology, Medical Institute

O.Ye. Antseferova, Belgorod State National Research University

Post-graduate student of the Department of Pharmacology, Medical Institute

T.I. Lokteva, Belgorod State National Research University

Post-graduate student of the Department of Pharmacology, Medical Institute

A.A. Dolzhikov, Belgorod State National Research University

Doctor of Medical Science; Head of the Department of Histology, Medical Institute

Загрузки

Опубликован

30.12.2015

Как цитировать

Gureev V, Antseferova O, Lokteva T, Dolzhikov A (2015) The effect of humoral factors released by hypoperfused placenta on fetal development. Research Results in Pharmacology 1(1): 34–37. https://doi.org/10.18413/2500-235X-2015-1-4-39-44

Выпуск

Раздел

Экспериментальная фармакология