Human recombinant erythropoietin gradient dosage influence on ischemic and reperfusion liver injury

Авторы

  • S.A. Alehin Kursk State Medical University
  • D.I. Kolmykov Kursk State Medical University
  • M.V. Pokrovskii Belgorod State National Research University

DOI:

https://doi.org/10.18413/2500-235X-2015-1-4-9-14

Аннотация

We investigate influence of human recombinant erythropoietin different dosage on blood flow velocity and morphological changes in liver during ischemic and reperfusion injury. It was proved what optimal preconditioning dosage is 50 IU/kg.

Ключевые слова:

ischemia, reperfusion, liver, blood flow, morphological changes

Библиографические ссылки

Emelianov R. A., Alehin S. A., Nazarenko D. P. Microcyrculation investigation by lazerdopplerflowmetry method in pancreatic gland during acute experimental pancreatitis. Kuban’s scientific bulletin. №1-2 (2007): P. 50-51.

Gernakova N.I., Alehin S. A., Kolmykov D.I. Preconditioning in ischemic and reperfusion liver injury. Scientific bulletin of BelSu. V.4(123), 17/1 (2012): P. 157-162.

Gernakova N.I., Alehin S. A., Pokrovsky M.V. Distant and direct ischemic preconditioning influence on NO stable metabolites dynamic at intestinal ischemia. Scientific bulletin of BelSu. V.4(123), 17/1 (2012): P. 163-167.

Penttild H.J., Lepojarvi M.V.K., Paivi К.et al. Ischemic preconditioning does not improve myocardial preservation during off-pump multivessel coronary operation. Circulation. Vol. 75. (2003): P. 1246-1252.

Qian Y, Liu Z, Geng X. Lack of protection of ischaemic preconditioning in the rat model of major hepatectomy with ischaemia reperfusion injury. Asian J Sur. Jul;31(3) (2008): P. 140-147. DOI: 10.1016/S1015-9584(08)60075-5.

Вклад авторов

S.A. Alehin, Kursk State Medical University

Phd in Medical Sciences, assistant, Department of Surgery

D.I. Kolmykov, Kursk State Medical University

Assistant, Department of Surgery

M.V. Pokrovskii, Belgorod State National Research University

Doctor of Medical Sciences, Professor; Department of pharmacology

Загрузки

Опубликован

30.12.2015

Как цитировать

Alehin S, Kolmykov D, Pokrovskii M (2015) Human recombinant erythropoietin gradient dosage influence on ischemic and reperfusion liver injury. Research Results in Pharmacology 1(1): 9–12. https://doi.org/10.18413/2500-235X-2015-1-4-9-14

Выпуск

Раздел

Экспериментальная фармакология