Is antibiotics overuse justified when immediate intervention is not possible? A rapid evidence review

Авторы

DOI:

https://doi.org/10.3897/rrpharmacology.7.77709

Аннотация

Introduction: This review revisits clinical use of antibiotics for most common acute oro-dental conditions; we aim to provide evidence governing antibiotics use when access to oral healthcare is not available, as during the ongoing outbreak of the severe acute respiratory syndrome coronavirus 2.

Materials and methods: In this rapid review, articles were retrieved after conducting a search on PubMed and Google Scholar. Relevant publications were selected and analyzed. Most recent systematic reviews with/without meta-analyses and societal guidelines were selected. Data were extracted, grouped, and synthesized according to the respective subtopic analysis.

Results and discussion: There was evidence supporting the use of antibiotics in common oro-dental conditions as temporary measure when immediate care is not accessible, such as in case of localized oral swellings as well as to prevent post-extraction complications. No sufficient evidence could be found in support of antibiotic use for pain resulting from pulpal origin.

Conclusion: Antibiotic use may be justified to defer treatment temporarily or reduce risk of complications in case of localized infection and tooth extraction, when no access to immediate dental care is possible.

Graphical abstract:

 

Ключевые слова:

antibacterial agents, antibiotics, COVID-19, drug misuse, odontogenic infection

Вклад авторов

Nour I. Ibrahim, Lebanese University

MD, Research Fellow at the American University of Beirut Medical Center, e-mail: nouribrahim5@hotmail.com, ORCID ID: https://orcid.org/0000-0002-0690-4401. The author conducted the literature search and primary scanning of the papers and engaged in manuscript writing.

Ziad E.F. Noujeim, Lebanese University

DDS, FICD, FEBOS, Oral and jaw surgeon and assistant clinical professor in the Department of Oral & Maxillofacial Surgery and Department of Oral Medicine and Maxillofacial Radiology at the Faculty of Dental Medicine, Lebanese University, email: ziadnari@hotmail.com, ORCID ID: https://orcid.org/0000-0002-7018-3987. The author conducted primary scanning of the papers and engaged in manuscript writing.

Georges Aoun, Lebanese University

DDS, DSO, Professor of oral medicine and chief of the Oral Medicine and Maxillofacial Radiology Department at the Faculty of Dental Medicine, Lebanese University, email: dr.georgesaoun@gmail.com, ORCID ID: https://orcid.org/0000-0001-5073-6882. The author conceptualized the review, interpreted studies and engaged in manuscript writing.

Abbass Z.R. El-Outa, American University of Beirut

DDS, DES, Surgical dentist in private practice and clinical researcher at the American University of Beirut and at “observe” group, email: abbass@abbass.org, ORCID ID: https://orcid.org/0000-0001-7738-4733. The author conceptualized the review, reviewed the final articles included, interpreted the results, and engaged in manuscript writing.

Загрузки

Опубликован

03.12.2021

Как цитировать

Ibrahim NI, Noujeim ZE, Aoun G, El-Outa AZ (2021) Is antibiotics overuse justified when immediate intervention is not possible? A rapid evidence review. Research Results in Pharmacology 7(4): 41–46. https://doi.org/10.3897/rrpharmacology.7.77709

Выпуск

Том 7 № 4 (2021)

Раздел

Обзорная статья