Pharmacotherapy of arterial hypertension: assessment of knowledge levels among students and practicing physicians. Results of the PHYSTARH-II Project
DOI:
https://doi.org/10.18413/rrpharmacology.11.559Аннотация
Introduction: Arterial hypertension (AH) is a significant risk factor for cardiovascular diseases and premature mortality. The aim of the study: To assess the level of knowledge and cognizance of physicians and medical students in a field of pharmacotherapy of AH.
Materials and Methods: This article analyzes the second phase (2019-2023) of the PHYSTARH project, a multicenter anonymous survey involving 494 therapeutic physicians from 10 Russian cities/regions and 426 students from 10 Russian and Kyrgyz universities. Comparisons were made with the previous phase (2017-2019) of student and physician research. Statistical methods included descriptive statistics, Kolmogorov-Smirnov, U-Mann-Whitney, Kruskal-Wallis, Pearson correlation, median test, ANOVA, and regression analysis (p<0.05).
Results: The study revealed that the knowledge levels among both students and physicians is not sufficiently high. Moreover, some questions showed a fatally low level of knowledge. The average level of correct answers in the second part of the survey (LCA) was 44.9% for students and 53.5% for physicians. The LCA for students in the previous phase was 57.7%, while the LCA for physicians (2017-2019) in the second part of the survey was 60%.
Conclusion: The common level of knowledge base among students and physicians regarding key aspects of AH is insufficient. It is essential to implement additional educational programs to fill the recognized knowledge gaps. The results of studies highlight the necessity of improving educational programs for medical specialists in the field of arterial hypertension. The lowest correct answers rates were found in questions regarding the use of acetylsalicylic acid in patients with AH. The highest correct response rate was recorded for a question about selecting the optimal drug for managing uncomplicated hypertensive crises.
Графическая аннотация

Ключевые слова:
educational pharmacoepidemiology, multicenter study, pharmacoepidemiological cross-section of specialists’ knowledge, knowledge assessment, real-world knowledge, surveying, medication errors, safety of pharmacotherapyБиблиографические ссылки
Balanova Yu, Drapkina O, Kutsenko V, Imaeva A, Kontsevaya A, Maksimov S, Muromtseva G, Kotova M, Karamnova N, Evstifeeva S, Kapustina A, Litinskaya O, Pokrovskaya M, Filichkina E, Ivlev O, Gomanova L, Doludin Yu, Efimova I, Borisova A, Nazarov B, Yarovaya E, Repkina T, Gonoshilova T, Kudryavtsev A, Belova N, Shagrov L, Samotrueva M, Yasenyavskaya A, Chernysheva E, Glukhovskaya S, Levina I, Shirshova E, Dorzhieva E, Urbanova E, Borovkova N, Kurashin V, Tokareva A, Ragino Yu, Simonova G, Khudyakova A, Nikulin V, Aslyamov O, Khokhlova G, Solovyova A, Rodionov A., Kryachkova O, Shamurova Yu, Tantsyreva I, Baryshnikova I, Ataev M, Radjabov M, Isakhanova M, Umetov M, Elgarova L, Khakuasheva I, Yamashkina E, Esina M, Kunyaeva T, Nikitina A, Savvina N, Spiridonova Yu, Naumova E, Keskinov A, Kashtanova D, Yudin V, Yudin S, Shalnova S (2023) Hypertension in the Russian population during the COVID-19 pandemic: sex differences in prevalence, treatment and its effectiveness. Data from the ESSE-RF3 study. Cardiovascular Therapy and Prevention [Kardiovaskulyarnaya Terapiya i Profilaktika] 22(8S): 3785 https://doi.org/10.15829/1728-8800-2023-3785 [in Russian]
Balanova Yu, Kontsevaya A, Myrzamatova A, Mukaneeva D, Khudyakov M, Drapkina O (2020) Economic burden of arterial hypertension in the Russian Federation. Rational Pharmacotherapy in Cardiology 16(3): 415–423. https://doi.org/10.20996/1819-6446-2020-05-03 [in Russian]
Balanova Yu, Shalnova S, Imaeva A, Kapustina A, Muromtseva G, Evstifeeva S, Tarasov V, Redko A, Viktorova I, Prishchepa N, Yakushin S, Boytsov S, Drapkina O (2019) Prevalence, awareness, treatment, and control of arterial hypertension in the Russian Federation (data from the ESSERF-2 observational study). Rational Pharmacotherapy in Cardiology 15(4): 450–466 https://doi.org/10.20996/1819-644 [in Russian]
Bontsevich R, Vovk Ya, Gavrilova A, Kirichenko A, Krotkova I, Kosmacheva E, Kompaniets O, Prozorova G, Nevzorova V, Martynenko I, Ketova G, Barysheva V, Maksimov M, Osipova O (2021) Drug therapy of arterial hypertension: assessment of the physicians’ basic knowledge. Final results of the PHYSTARH project. Systemic Hypertension 18(2): 80–87 https://doi.org/10.26442/2075082X.2021.2.200884 [in Russian]
Bontsevich R, Vovk YaR, Kotlyarova V, Batishcheva G, Goncharova N, Cherenkova O, Ketova G, Barysheva V, Bikkinina G (2022) Drug therapy of arterial hypertension: assessment of the senior students’ basic knowledge. Final results of the PHYSTARH project. Systemic Hypertension 19(2): 5–10. https://doi.org/10.38109/2075-082X-2022-2-5-10 [in Russian]
Bontsevich RA (2024) Educational pharmacoepidemiology and “Real-World Knowledge”. Real-World Data & Evidence [Real'naya Klinicheskaya Praktika: Dannye i Dokazatel'stva] 4(4): 44–52 https://doi.org/10.37489/2782–3784myrwd-062 [in Russian]
Chazova I, Chikhladze N, Blinova N, Belaya Zh, Danilov N, Elfimova E, Litvin A, Rozhinskaya L, Sviridenko N, Shvetsov M, Azizov V, Grigorenko E, Mit’kovskaja N, Mustafaev I, Polupanov A, Sarybaev A, Hamidullaeva G (2023) Eurasian clinical guidelines for the diagnosis and treatment of secondary (symptomatic) forms of arterial hypertension. Eurasian Heart Journal [Evraziiskij Kardiologicheskii Zhurnal] (1): 6–65. https://doi.org/10.38109/2225-1685-2023-1-6-65 [in Russian]
Chazova I.E, Zhernakova YuV (2019) Diagnosis and treatment of arterial hypertension [Guidelines]. Systemic Hypertension [Sistemnye Ghipertenzii] 16(1): 6–31. https://doi.org/10.26442/2075082X.2019.1.190179 [in Russian]
Russian Society of Cardiology (2020). Arterial hypertension in adults. Clinical guidelines 2020. Russian Journal of Cardiology. 2020;25(3):3786. (In Russ.):2618‑7620https://scardio.ru/content/Guidelines/Clinic_rek_AG_2020.pdf [in Russian]
Kobalava J, Konradi A, Nedogoda S, Shlyakhto E, Arutyunov G, Baranova E, Barbarash O, Boytsov S, Vavilova T, Villevalde S, Galyavich A, Glezer M, Grineva E, Grinshtein Y, Drapkina O, Zhernakova Y, Zvardau N, Irtyuga O, Kislyak O, Koziolova N, Kosmacheva E, Kotovskaya Y, Bobkova N, Libis R, Lopatyn Y, Nebiridze D, Nedoshivin A, Nikulina S, Ostroymova O, Oshchepkova E, Ratova L, Salasyuk A, Skibitsky V, Tkacheva O, Troitskaya E, Chazova I, Chesnikov A, Chumakova G, Shalnova S, Shestakova M, Yakushin S, Yanishevsky S (2024) Arterial hypertension in adults. Clinical recommendations. Russian Journal of Cardiology 29(9): 6117 https://doi.org/10.15829/1560-4071-2024-6117 [in Russian]
Kobaleva Z, Konradi A, Nedogoda S, Shlyakhto E, Arutyunov G, Baranova E, Barbaraash O, Boytsov S, Vavilova T, Villevalde S, Galyavich A, Glezer M, Grineva E, Grinshtain Yu, Drapkina O, Zhernakova Yu, Zvartau N, Irtyuga O, Kislyak O, Koziolova N, Kosmacheva E, Kotovskaya Yu, Bobkova N, Libis R, Lopatkin Yu, Nebiridze D, Nadoshivin A, Nikulina S, Ostrova O, Oshchepkova E, Ratova L, Salasyuk A, Skibitsky V, Tkacheva O, Troitskaya E, Chazova I, Chesnikova A, Chumakova G, Shalnova S, Shestakova M, Yakushin S, Yanishevsky S (2024) Arterial hypertension in adults. Clinical guidelines. Russian Journal of Cardiology [Rossijskij Kardiologicheskij Zhurnal] 29(9): 6117 https://doi.org/10.15829/1560-4071-2024-6117 [in Russian]
Laguta P, Karpov Yu (2007) Application of acetylsalicylic acid in patients with arterial hypertension. Russian Journal of Cardiology [Rossiiskii Kardiologicheskii Zhurnal] 20: 1489. [in Russian]
Leonova M, Belousov D, Shteinberg L, Galitskiy A, Belousov Yu (2010) First results of the pharmacoepidemiological study of arterial hypertension, PIFAGOR III. Quality Clinical Practice [Kachestvennaya Klinicheskaya Praktika] (1): 54–60. [in Russian]
Melekhov A, Ryazantseva E (2013) Acetylsalicylic acid in primary prevention among patients with arterial hypertension. Russian Journal of Cardiology [Rossiiskii Kardiologicheskii Zhurnal] (5): 81-87 https://doi.org/10.15829/1560-4071-2013-5-81-87 [in Russian]
Rotar O, Ilyanova I, Boyarinova M, Moguchaya E, Tolkunova K, Dyachkov V, Rubanenko O, Rubanenko A, Gaberman O, Gubareva E, Pomogaibo B, Dolya E, Kaliberdenko V, Avdeeva I, Tomashevskaya Yu, Falkovskaya A, Manukyan M, Solonskaya E, Vtorushina A, Khunkhinova S, Tsareva V, Molokoedova L, Petrova M, Kaskaeva D, Romanova I, Danilova L, Evsyukov A, Tutyrina O, Tepnadze L, Yakunchenko T, Mevsha O, Sharapova Yu, Chernykh T, Syomkina E, Tsygankova O, Protasov K, Fedorishina O, Makeeva E, Smolkina Y, Nikishina D, Verushkina A, Smirnova E, Belenikina Ya, Bikushova I, Derevyanchenko M, Fedotov V, Shaposhnikova M, Sereda D, Kartashova E, Zheleznyak E, Rakhmatullina D, Kiseleva L, Evsevieva M, Sergeeva O, Kudryavtseva V, Zavyalova A, Slezova V, Kitalaeva K, Artemov N, Tanicheva A, Konradi A, Shlyakhto E (2024) All-Russian screening for hypertension: results. Russian Journal of Cardiology [Rossiiskii Kardiologicheskii Zhurnal] 29(5): 5931. https://doi.org/10.15829/1560-4071-2024-5931 [in Russian]
Sobhy M, Eletriby A, Ragy H (2024) ACE inhibitors and angiotensin receptor blockers for the primary and secondary prevention of cardiovascular outcomes: Recommendations from the 2024 Egyptian Cardiology Expert Consensus in Collaboration with the CVREP Foundation. Cardiology and Therapy 13: 707–736. https://doi.org/10.1007/s40119-024-00381-6
Soboleva M, Slobodenyuk E (2011) Advantages of combined therapy for arterial hypertension based on modern research. Far Eastern Medical Journal [Dal'nevostochnyy Meditsinskii Zhurnal] 3: 81–84. [in Russian]
Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, Clement D, Coca A, De Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen S, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder R, Shlyakhto E, Tsioufis K, Aboyans V, Desormais I (2018) Practice guidelines for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension. Blood Press 27(6): 314–340 https://doi.org/10.1080/08037051.2018.1527177
Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I; Authors/Task Force Members (2018) 2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension. Journal of Hypertension 36(10): 1953–2041. https://doi.org/10.1097/HJH.0000000000001940 [PubMed]
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Copyright (c) 2025 Bontsevich RA, Kosimova NSh, Chernyadyeva TI, Batishcheva GA, Nevzorova VA, Tsygankova OV, Ketova GG, Prozorova GG, Kompanets OG, Tilekeeva UM, Bikkinina GM, Luchinina EV, Maksimov ML

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